Secrets about latex allergies you never knew The basics People with latex allergies have an immune response to the natural rubber latex that is found in gloves, balloons and other items. There are three types of reactions to latex. The most severe, life-threatening is when a person has a full-on reaction and develops hives asthma and maybe even anaphylaxis. The next kind is a rash reaction on the skin when in contact with latex. The third is an irritation that …